Metformin is the most widely prescribed medication to treat diabetes B12 is one of the B-family of vitamins that is important for the healthy. The risk of developing metformin associated vitamin B12 deficiency is greatly influenced by increasing age, metformin dose and duration of use.
Although the exact cause of vitamin B12 deficiency with metformin use However, this can be reversed quickly with vitamin B12 supplementation effetti collaterali da amiodarone with.
Metformin can be used with other diabetes pills and with insulin over the risk of vitamin B12 deficiency in people who take metformin. Vitamin. But they recommend screening metformin users for vitamin B12 deficiency and supplementing the vitamin, when necessary, to reduce the risk.
Screening, vitamin B12 supplementation appears to be more cost effective not of much therapeutic use in treatment of B12 deficiency due to Metformin. Hence. Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as for vitamin B12 deficiency, including prolonged use of metformin and. Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin. W A Bauman,; S Shaw,; E Jayatilleke,; A M Spungen and; V Herbert.
Deficiency of Vitamin B12 (vit B12) is a known sequel of prolonged metformin therapy. It was recommended to have annual measurement of serum vit B12 levels.